Release samples are not looped in any of S3 guitars. Only tremolo articulations are looped, if it was sampled for a particular guitar.
The A note in question just sounds like the particular way the guitarist fingered that fret. It is what it is, it won't be changed, the guitar won't be sampled again. Of course, if you put amp gain at 10 you can expect all the noise you're really getting, it would be like that on a real amp too (or even worse).